Kris Jenner admits Ozempic made her ‘really sick,’ couldn’t work during trial run

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Kris Jenner finally admitted she tried Ozempic when nobody was using it, but the experience was catastrophic for the 70-year-old Kardashian matriarch. During a May 5 podcast appearance, she revealed the weight-loss drug made her too sick to work. She’s since switched to a surprising alternative that changed everything.

🔥 Quick Facts

  • The Confession: Kris tried Ozempic years ago before it became mainstream, but nausea forced her to stop immediately
  • Her Words: The momager told Dr. Thais Aliabadi, “I can’t work anymore, I’m so sick, I can’t like nauseous”
  • Game Changer: Kris switched to peptide injections and supplements, which gave her much more energy without side effects
  • Current Strategy: She now gets blood work every three months and focuses on hormone balance for optimal health

Kris Jenner’s Shocking Ozempic Trial Run Went Horribly Wrong

The famous reality TV momager opened up about her early Ozempic experiment on the “She MD” podcast. Kris revealed she was among the first to try the GLP-1 drug before it became a cultural phenomenon. “I tried it,” she explained to co-host Mary Alice Haney. “We tried it once when no one knew what it was and it made me really sick.”

The founder of the Kardashian-Jenner empire didn’t mince words about how severe the nausea was. She remembered calling her personal physician Dr. Thais Aliabadi in distress, telling her she couldn’t perform even basic work duties. The medication’s side effects were so intense that Kris had to abandon the drug almost immediately.

Why Ozempic Became Too Much for the Momager

Ozempic is a Type 2 diabetes medication that’s increasingly used off-label for rapid weight loss in Hollywood. However, the nausea side effects are among the most commonly reported issues. Kris experienced severe nausea that made it impossible to continue her work schedule. She described the crisis moment to Dr. Aliabadi, saying she urgently needed something different.

The mother of six children emphasized that she simply couldn’t function while taking Ozempic. Her reaction stands in contrast to other celebrities who’ve tolerated the drug’s side effects. Kris never intended to continue with the medication after her initial trial, making her switch strategy quick and decisive.

From Ozempic Disaster to Game-Changing Peptides

Approach Details
Former Method Short trial of Ozempic resulted in severe nausea
Current Method Peptide injections combined with targeted supplements
Energy Impact Extra hours of energy at night and overall improved stamina
Added Benefits Improved hair, nails, skin, and hormone optimization

With Dr. Aliabadi’s guidance, Kris found her perfect formula. Injectable peptides (short chains of amino acids) replaced Ozempic entirely. “I realized that a peptide injection was really great for me,” the momager shared enthusiastically. She follows the peptide shots with specific supplements like fish oils and omega-3s that her doctor recommends.

“I felt like I had more energy. And of course, it’s good for hair, and nails, and skin and all of that stuff. And that was a game changer. That actually bought me an extra couple hours at night.”

Kris Jenner, Momager and Kardashian-Jenner Matriarch

How Kris Jenner Maintains Peak Health at 70

The Kardashian family matriarch is incredibly proactive about preventative health care. Beyond peptides and supplements, Kris gets blood work drawn every three months to monitor hormone levels. She’s especially focused on thyroid function and hormone balance after turning 45, recognizing how critical these metrics became as she aged.

Full-body MRIs and comprehensive health screenings are regular parts of her routine. Kris also underwent a viral facelift in 2025, which she credits Dr. Steven Levine for executing perfectly. She recently defended the results on her daughter Khloé’s podcast, calling them transformative and affirming her decision entirely.

What Does Kris Jenner’s Ozempic Confession Mean for Other Celebrities?

Kris Jenner’s honesty about Ozempic’s serious side effects matters for public health conversations. While many celebrities have praised GLP-1 medications, her experience highlights that weight-loss drugs simply don’t work for everyone. The nausea, inability to work, and overall quality of life impacts are real concerns that deserve serious consideration.

Her pivot to peptides and supplements represents an emerging trend among high-profile figures seeking safer alternatives. Unlike Ozempic, peptides remain less studied by medical researchers, but Kris has made it clear they aligned better with her body and lifestyle needs. Her story encourages others to work closely with physicians rather than following celebrity trends blindly.

Sources

  • People.com – Kris Jenner’s full interview about Ozempic trial and peptide switch with direct quotes
  • InStyle Magazine – Detailed podcast appearance transcript and health regimen insights
  • E! News – Breaking coverage of momager’s Ozempic confession and side effects revelation

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